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The Battle of Guilford Court House was fought on March 15, 1781, during the American Revolutionary War, at a site which is now in Greensboro, the seat of Guilford County, North Carolina. A 2,100-man British force under the command of Lieutenant General Charles Cornwallis defeated Major General Nathanael Greene's 4,500 Americans.

Guilford Courthouse National Military Park, at 2332 New Garden Road in Greensboro, Guilford County, North Carolina, commemorates the Battle of Guilford Court House, fought on March 15, 1781. This battle opened the campaign that led to American victory in the Revolutionary War. The losses by the British in this battle contributed to their surrender at Yorktown seven months later.

Guilford Court House, North Carolina, was the county seat of Guilford County before being replaced by Greensboro in 1808. It no longer exists as an identifiable community, having been absorbed by Greensboro. In 1781, it was the site of the Battle of Guilford Court House, which is now commemorated at Guilford Courthouse National Military Park.