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The Battle of San Romano was fought on June 1, 1432, in San Romano, some 30 miles outside Florence, between the troops of Florence, commanded by Niccolò da Tolentino, and Siena, under Francesco Piccinino. The outcome is generally considered favourable to the Florentines, but in the Sienese chronicles it was considered a victory.

The Sanctuary of the Madonna di San Romano, also known as the Sanctuary of Mother Mary of the Divine Grace, is a renaissance-style, Marian sanctuary and Franciscan convent, located in the frazione of San Romano in the territory of the town of Montopoli in Val d'Arno, province of Pisa, region of Tuscany, Italy.