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Downtown Jacksonville is the historic core and central business district (CBD) of Jacksonville, Florida USA. It comprises the earliest area of the city to be developed and is located in its geographic center along the narrowing point of the St. Johns River. There are various definitions of what constitutes Jacksonville's downtown; the one used by the city government and other entities defines it as including eight districts: the Central Core (or Northbank), the Southbank, LaVilla, Brooklyn, the Working Waterfront, the Cathedral, the Church, and the Entertainment & Sports District.

The St. Elmo W. Acosta Bridge spans the St. Johns River in Jacksonville, Florida on a fixed span. It is named for City Councilman St. Elmo W. Acosta, who convinced voters to approve a $950,000 bond issue for the original bridge at the site. It carries a total of six lanes of SR 13 with the two-track Jacksonville Skyway in the median and sidewalks on the outside.

The CSX Transportation Building is a 251 feet (77 meters) high-rise office building located in Jacksonville, Florida. Completed in 1960, the building currently serves as headquarters for CSX Corporation. The building is located in the Northbank area of Downtown Jacksonville, along the banks of the St.

The FEC Strauss Trunnion Bascule Bridge is a double track railroad bridge spanning the St. Johns River in Jacksonville, Florida.Completed in 1925 by the Florida East Coast Railway, this structure replaced a single-track swing bridge which opened on January 5, 1890. The current structure is a simple truss bridge with plate girder approaches and a bascule lift allowing ships to pass.

Bryan-Gooding Planetarium in the Alexander Brest Science Theatre is a planetarium in the Museum of Science and History in Jacksonville, Florida, U.S. It was built in 1988 and featured a 60-foot-diameter (18 m) dome-shaped projection screen, JBL stereo sound system, and a Zeiss Jena Optical mechanical planetarium star projector.

The Main Street Bridge, officially the John T. Alsop Jr. Bridge, is a bridge crossing the St. Johns River in Jacksonville, Florida. It was the second bridge built across the river. It carries four lanes of traffic, and is signed as US 1/US 90 (SR 5/SR 10). A lift bridge, it opened in July 1941 at a cost of $1.5 million.

Two Prudential Plaza is a 305.02 ft (92.97 m) skyscraper in Jacksonville, Florida. Located in the Southbank area of Downtown, the building currently serves as the regional office of Prudential Financial and is also home to other companies, including FIS and Interline Brands. The 21-floor structure was designed by KBJ Architects and completed in 1985.

The Jacksonville Landing shooting, also known as the Jacksonville shooting, was a mass shooting that occurred at a video game tournament for the video game Madden NFL 19 in Jacksonville Landing, Jacksonville, Florida, on August 26, 2018, at about 1:30 pm (EDT). A lone gunman, David Katz, shot and killed two people and injured another ten before committing suicide.

San Marco station is a Jacksonville Skyway people mover station in Jacksonville, Florida. It is located at the corner of San Marco Boulevard and Mary Street in the Southbank area of Downtown Jacksonville. Nearby points of interest include the Museum of Science and History and Friendship Fountain Park.

One Enterprise Center is a 299.00 ft (91.14 m) skyscraper in Jacksonville, Florida. Located in the Northbank area of Downtown, tenants include Rayonier and CBRE Group. The building also shares a lobby with an adjacent Omni Hotel. The 21-floor structure was designed by Clark Tribble Harris & Li Architects and completed in 1986.