The University of California, Irvine Arboretum (UCI Arboretum or UC Irvine Arboretum) is a 12.5-acre botanical garden and arboretum, part of the University of California, Irvine in Irvine, California. It is located north of the main UCI campus, on Campus Drive in Irvine, near the San Joaquin Wildlife Sanctuary and the Upper Newport Bay.