Ponte Sisto is a bridge in Rome's historic centre, spanning the river Tiber. It connects Via dei Pettinari in the Rione of Regola to Piazza Trilussa in Trastevere. The construction of the current bridge occurred between 1473 and 1479, and was commissioned by Pope Sixtus IV (r. 1471-84), after whom it is named, from the architect Baccio Pontelli, who reused the foundations of a prior Roman bridge, the Pons Aurelius, which had been destroyed during the early Middle Ages.