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Museo de Arte de Ponce (MAP) is an art museum located on Avenida Las Américas in Ponce, Puerto Rico. It houses a collection of European art, as well as works by Puerto Rican artists. The museum contains one of the most important Pre-Raphaelite collections in the Western Hemisphere, holding some 4,500 pieces of art distributed among fourteen galleries.

The Carnaval de Ponce (English: Ponce Carnival), officially Carnaval Ponceño, is an annual celebration held in Ponce, Puerto Rico. The celebration lasts one week and it ends on the day before Ash Wednesday. Thus, it is generally held in February and sometimes in March. It is one of the oldest carnivals of the Western Hemisphere, dating back to 1858.

The Feria de Artesanías de Ponce (English: Ponce Crafts Fair), formally, Feria de Artesanías y Muestra de Arte de Ponce (Ponce Crafts Fair and Arts Expo), is an event that takes place every year in Ponce, Puerto Rico, where artists, craftsmen and artisans showcase their products. The products showcased are traditionally hand-made and in small quantities.

The Carnaval de Vejigantes, officially Carnaval de Vejigantes de La Playa de Ponce, is an annual celebration held at Barrio Playa in Ponce, Puerto Rico. The celebration, which commonly lasts three to five days, generally takes place in late January or early February. It started in 1991. It takes place at Parque Lucy Grillasca on PR-585 in Barrio Playa.

Caribbean School is a private, college preparatory day school in Ponce, Puerto Rico. Its curriculum covers grades from pre-kindergarten through twelfth grade.

Día Mundial de Ponce (Ponce World Day) is a cultural celebration held in Ponce, Puerto Rico, every year during the month of September. The celebration actually starts the Monday before Labor Day with various evening-time cultural festivities. It then culminates with the grand parade that takes place on the Sunday before Labor Day.

Hospital Damas, formerly called Santo Asilo de Damas, is a 331-bed teaching hospital in Ponce, Puerto Rico.

The Museo del Autonomismo Puertorriqueño (English: Museum of Puerto Rican Autonomism) is a small museum in Ponce, Puerto Rico, that showcases the political history of Puerto Rico with an emphasis on the contributions made by the municipality of Ponce and its residents. The museum was established on 7 September 2006.

The Museo de Arqueología de la Pontificia Universidad Católica de Puerto Rico (Museum of Archaeology of the Pontifical Catholic University of Puerto Rico) is a museum of archaeology located at the Pontificia Universidad Católica de Puerto Rico (PUCPR) main campus on Avenida Las Américas in Ponce, Puerto Rico.

The Pontifical Catholic University of Puerto Rico School of Architecture is located in the Ponce Historic Zone, across from Plaza Las Delicias. Together with the School of Law, it is one of two semi-autonomous professional colleges of the Pontifical Catholic University of Puerto Rico (PCUPR) in the city of Ponce, Puerto Rico.